The fact of Paul's sorrow is stated here; the cause of it is revealed in Romans 9:3. Weiss remarks on the triple climax: λύπη being intensified in ὀδύνη, μεγάλη in ἀδιάλειπτος, and μοι in τῇ καρδίᾳ μου. Paul cannot find words strong enough to convey his feeling.

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Old Testament