Revelation 12:12

12   Therefore rejoice, ye heavens, and ye that dwell in them. Woe to the inhabiters of the earth and of the sea! for the devil is come down unto you, having great wrath, because he knoweth that he hath but a short time.

When the devil is cast out of heaven he will come with great wrath against humans. He knew from the start that humans were created to replace his angels. He did everything he could to keep the human race from qualifying. Even after the Messiah came he tried to deceive Him into using His divine powers to disqualify Him as a human and as mankind’s kinsman redeemer (Matthew 4:1-11).

Now that Satan has lost the battle in heaven he will use his angels to deceive and destroy mankind on earth. He will be very aware that Jesus is about to return with His saints in a very short time and he will do everything in his power to give Him a planet with no one alive. Jesus Himself said, unless those days be shortened no flesh would be saved but for the sake of the elect those days will be shortened (Matthew 24:22). Satan will make Jews the scapegoats and the focal point to lead mankind to its own destruction.

In Revelation 12:12 there is only one woe mentioned by the angel because the other two are now over with. The third woe lasts the entire second half of Daniel’s final week of years. The third woe will span a 3 ½ year period. It will start with the persecution of all mankind who will not worship the Beast as God and it will end with the seven vial judgments from God.