To tread on serpents and scorpions; to tread on literal serpents and scorpions without harm, and to overcome wicked men, who are like serpents and scorpions in character.

Nothing shall by any means hurt you; the chief reference of these words is to the spiritual victory which Christ gives his servants over all evil, of which the outward deliverances sometimes vouchsafed to them in this world are symbols and pledges. Compare Romans 8:28; Romans 8:37. Christ is able to give his ministers all the aid which they need for the discharge of their duties. In his name and strength they may commence their work, and go on from conquering to conquer, till every knee shall bow, and every tongue confess that he is Lord, to the glory of God the Father.

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Old Testament