Genesis 21:17

Called out of heaven— i.e.. the air or clouds: arise, (Genesis 21:18.) lift up the lad, and hold him in thine hand: the Hebrew is, and strengthen thy hand (or thou shalt strengthen thy hand) in, or by him, because I will make him a great nation; a promise which must necessarily have afforded her great comfort. And in this view the words contain a comfortable exhortation to Hagar, Arise, and raise up the lad, free from all fears of his death; and, grow strong in him, be assured thou shalt be supported and strengthened through him, whom I will certainly make a great nation.