Carchemish, or Charchemish (kär-ke'mĭsh), citadel of Chemosh. A chief city of northern Syria, on the Euphrates, where a great and decisive battle was fought, in which Nebuchadnezzar defeated Pharaoh-necho. 2 Chronicles 35:20, 2 Kings 23:29, Jeremiah 46:2, in b.c. 605.