I had no rest in my spirit, because I found not Titus my brother: but taking my leave of them, I went from thence into Macedonia.

No rest in my spirit - rather 'no rest for my spirit' (). As here his "spirit" had no rest, so in , his "flesh." His "spirit" - not from mere human impulse, but under the Holy Spirit-hence concluded that it was not necessary to avail himself of the "door" of usefulness at Troas any longer.

Taking my leave of them - the disciples at Troas.

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