Galatians 3:4

Have ye suffered so many things in vain? The reference is, as in Galatians 3:2, to persecutions experienced by them at the time of their conversion. Though we have no record of these, yet, as Bp. Lightfoot remarks, the history "is equally silent on all that relates to the condition of the Galatian Churches; and while the converts to the faith in Pisidia and Lycaonia on the one side (Acts 14:2; Acts 14:5; Acts 14:19; Acts 14:22), and in proconsular Asia on the other (2 Corinthians 1:8; Acts 19:23, sqq.), were exposed to suffering, it is improbable that the Galatians alone should have escaped". He adds, "If …, as is most likely, the Jewswere the chief instigators in these persecutions St. Paul's appeal becomes doubly significant". Some would render, -Have ye experienced so many things?" i.e. (1) so many spiritual blessings (which would make the question nearly a repetition of Galatians 3:2) or (2) such trials and such mercies.

if it be yet in vain -if it be indeed in vain". This is added in the exercise of that charity which -hopeth all things".