Mark 15:23

they gave him More literally, they offered Him.

wine mingled with myrrh It was a merciful custom of the Jews to give those condemned to crucifixion, with a view to producing stupefaction, a strong aromatic wine. Lightfoot tells us (Hor. Heb. ii. 366) it was the special task of wealthy ladies at Jerusalem to provide this potion. The custom was founded on Rabbinic gloss on Proverbs 31:6, "Give strong drinkto him that is perishing, and wineto those whose soul is in bitterness."

but he received it not The two malefactors, who were led forth with Him, probably partook of it, but He would take nothing to cloud His faculties.