Mark 1:35

πρωῒ, early, an elastic word, the last watch from three to six, defined more exactly by ἔννυχα λίαν = much in the night, at the beginning of the watch, or at the dark hour before dawn. ἔννυχα is the neuter plural of ἔννυχος, nocturnal, used as an adverb (here only). ἀναστὰς, etc.: He rose up, went out of Capernaum, went away to a desert, solitary place, and there engaged in prayer. It was a kind of flight from Capernaum, the scene of those remarkable occurrences; “flight from the unexpected reality into which His ideal conception of His calling had brought Him,” Holtz., H. C. The real reason of the flight was doubtless a desire to preach in as many synagogues as possible before the hostility of the scribes, instinctively dreaded, had time to act obstructively. Jesus had a plan of a preaching tour in Galilee (vide Mark 1:38), and He felt He could not begin too soon. He left in the night, fearing opposition from the people.