We are debtors - We owe it as a matter of solemn obligation. This obligation arises,

  1. From the fact that the Spirit dwells in us;
  2. Because the design of his indwelling is to purify us;
  3. Because we are thus recovered from the death of sin to the life of religion; and he who has imparted life, has a right to require that it be spent in his service.

To the flesh - To the corrupt propensities and passions. We are not bound to indulge them because the end of such indulgence is death and ruin; Romans 7:21. But we are bound to live to God, and to follow the leadings of his Spirit, for the end is life and peace; Romans 7:22. The reason for this is stated in the following verse.

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