Revelation 8:11

And the name of the star is called Wormwood,.... Because of the bitter afflictions, sorrows, and distresses which it was the instrument of; just as Naomi called herself Mara, because the Almighty had dealt bitterly with her, Ruth 1:20;

and the third part of the waters became wormwood; that is, the inhabitants of the provinces and cities belonging to the Roman empire were afflicted with grievous and bitter afflictions and calamities; so great distresses are called wormwood, and waters of gall given to drink, Jeremiah 9:15;

and many men died of the waters, because they were bitter; through the barbarities and cruelties of these savage people, who afflicted the empire: there seems to be an allusion to Exodus 15:23.