Thirst thurst (tsama', verb tsame'; dipsao, dipsos, dipsa): One of the most powerful natural appetities, the craving for water or other drink. Besides its natural significance, thirst is figuratively used of strong spiritual desire. The soul thirsts for God (Psalms 42:2, Psalms 63:1). Jesus meets the soul's thirst with water of life (John 4:13, John 6:35, John 7:37). It is said of the heavenly bliss, "They shall hunger no more; neither thirst any more" (Revelation 7:16, Revelation 7:17; compare Isaiah 49:10).