Nor because they are Abraham's seed, are they all τέκνα, i.e., children in the sense which entitles them to the inheritance, Romans 4:11; Romans 8:17. God from the very first made a distinction here, and definitely announced that the seed of Abraham to which the promise belonged should come in the line of Isaac not of Ishmael, though he also could call Abraham father. Ἐν Ἰσαὰκ κληθήσεταί σοι σπέρμα = Genesis 21:12, LXX. The words literally mean that in the line of Isaac Abraham should have the posterity which would properly bear his name, and inherit the promises made to him by God. Isaac's descendants are the true Abrahamidae.

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Old Testament