LUKE—NOTE ON Luke 1:35 The Holy Spirit will perform a great miracle, so that Mary will become pregnant without having sexual relations with a man. Therefore indicates that Jesus’ holiness comes from his being conceived by the Holy Spirit. He did not inherit a sinful nature from Adam (see 2 Corinthians 5:21; Hebrews 4:15; 1 Peter 2:22; 1 John 3:5; by contrast, Psalms 143:2; Ephesians 2:3).

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